Chronic pain, defined as pain persisting for more than three to six months, affects millions globally, significantly diminishing quality of life. Unlike acute pain, which signals injury or illness and typically resolves, chronic pain becomes a condition in itself, often without an identifiable cause or persisting long after the initial injury has healed. It manifests […]
The human body possesses an intricate regulatory network known as the endocannabinoid system (ECS), a crucial player in maintaining homeostasis across numerous physiological processes, including pain modulation, mood, appetite, and sleep. This complex system comprises endogenous cannabinoids (endocannabinoids) like anandamide (AEA) and 2-arachidonoylglycerol (2-AG), cannabinoid receptors (primarily CB